Geriatrics & Aging

Genetics of Ageing

The process of aging refers to the decline of an organism's structure and function, in which molecular and cellular changes have different effects on an individual level over a lifetime.

Genetics of aging is generally related with life extension associated with genetic mutations, rather than with accelerated aging diseases that lead to reduction in lifespan. Aging affects physiological functions and can be defined as the accumulation of damage to molecules, cells, and tissues over a life; It often reduces the body's ability to maintain homeostasis under stressful conditions and increases the risk of many diseases (cancer, cardiovascular and neurodegenerative disorders) and premature mortality.